Psychedelics and the Inner Healer: Myth or Mysticism?

2 min read · 20.7.2025

What, exactly, makes psychedelic-assisted therapy therapeutic?

In recent years, researchers have found that MDMA reduces activity in the amygdala, increases activity in the frontal cortex, and increases connectivity between the amygdala and the hippocampus, where memories are put into long-term storage. 

“Those are good explanations, but none of that is really filtered down to how you do the therapy differently,” Doblin says. 

Doing the therapy differently, however, is the exact platform on which MAPS has sold itself. 

“Inner healing intelligence” — which MAPS’ treatment manual defines as “a person’s innate capacity to heal the wounds of trauma” — seems intuitive enough. After all, cuts and scrapes heal on their own without direct intervention from the mind, so couldn’t your mind “get out of its own way,” through ego dissolution or some similar mechanism, to help facilitate emotional healing?

MAPS’ treatment strategy is based on the assumption that it can. 

“This very process of surrendering ego/directed functions to self/inner healer may be the method of therapeutic action that is so hard to come by without the help of MDMA.”

Critics have warned that assuming an “inner healer” could lead therapists and participants to interpret distress as evidence of healing, even when harm may be occurring.

Doblin is aware of such criticisms within the science community.

“‘Oh, this inner healing intelligence. It’s woo, woo. It’s not scientific.”


Someone took this apparently “woo-woo” therapeutic idea and began trying to formulate and investigate it scientifically.

In a post last year on X, the neuroscientist Robin Carhart-Harris wrote: “Can someone quote me something from a book or in academic literature referring to the inner healing mechanisms of psychedelic therapy?” 

Several months later, he posted: “A small step on a brave journey to consider & examine the validity of the ‘inner healer’ phenomenon in context of psychedelics,” sharing his new paper on the topic, titled, “Psychedelics and the inner healer: myth or mechanism?” Carhart-Harris wrote that he “does not see it as a mystical/supernatural phenomenon at all.”

Reference:

Saga Briggs. Inside the Battle for FDA Approval of MDMA Therapy. Big Think. 27.12.2024.

Joseph Peill et al. Psychedelics and the “inner healer”: Myth or mechanism? 2024.